The Santa Cruz River is a culturally and ecologically significant river in southern Arizona. Though river conditions have improved over the last decade, its rank of #4 on the “America’s Most Endangered Rivers of 2024” list points to the fragility of the system and the work that is still needed. Sonoran Institute and partners are working to annually report on river conditions, engage the community in educational and stewardship activities, and find long-term protection of the river and the numerous benefits provided to wildlife and communities from Mexico to Marana.